Sadržaj ukupnih fenola, antioksidativna i antimikrobna aktivnost Silene sendtneri Boiss. (Caryophyllaceae)
DOI:
https://doi.org/10.54652/rsf.2022.v52.i1.367Sažetak
U ovoj studiji urađena je procjena ukupnog sadržaja fenola (TPC) i flavonoida (TFC) te antioksidativnog i an-timikrobnog djelovanja hidrometanolnih ekstrakata iz cvasti, stabljike, rizoma i sjemenki Silene sendtneri(Sendtnerova pušina, Caryophyllaceae). TPC, TFC i antioksidativna aktivnost (DPPH; 2,2-difenil-1-pikrilhidrazil) određeni su UV/VIS spektrofotometrijom. Antimikrobna aktivnost procijenjena je protiv odabranih testnih mikroorganizama (Staphylococcus epidermididis, Staphylococcus aureus subsp. aureus, Salmonella abony i Esche-richia coli, te Candida albicans) pomoću disk difuzijskog testa. Cvasti su imale najviši (11,587 mg GAEg-1 SM), a rizom najniži ukupni sadržaj fenola (TPC) (2,017 mg GAEg-1 SM). Najbogatiji sa ukupnim flavonoidima (TFC) bili su ekstrakti cvasti (69,824 mg CEg-1 DW), dok TFC nije detektovan u ekstraktu rizoma. Najveću antioksi-dativnu aktivnost (IC50; 20,51%) imao je ekstrakt stabljike, a najmanju rizoma (61,89%). Svi ekstrakti su poka-zali umjerenu antibakterijsku aktivnost samo protiv Staphylococcus epidermididis, te nisku aktivnost protiv tri preostala testirana organizma. Antifungalna aktivnost ekstrakata cvasti i rizoma bila je umjerena. Dobiveni re-zultati daju osnovu za daljnja istraživanja različitih ekstrakata S. sendtneri, koji mogu biti potencijalni prirodni antioksidanti i antimikrobni agensi.
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Copyright (c) 2022 Fatima Pustahija, Sabina Rastoder, Rasim Duraković Duraković, Mirel Subašić, Neđad Bašić, Adisa Parić
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